- Enzymes order like a floors order in a building: 11b, 21, 17a
- Deficiency increase the upper floor enzyme:
- 11b deficiency increases 21, and 17a
- 21 deficiency increases 17a
- ALL deficiencies have:
- Increased ACTH
- Decreased Cortisol
- When Aldosterone is increased -> Na increased vs K decreased (opposite)
- If Na increases = Blood pressure increases = fluid retention
- K is H brother and pH enemy -> K increases = pH decreases
Funny and Creative Mind Maps & Mnemonics that really help you better understand the magic and abstract medical world. Specially for USMLE Step1 students... Don't forget to buy your First Aid Step 1 Book, watch the videos with your Fantabolous MindMaps printed. Enjoy this blog!
Saturday, December 14, 2013
Adrenal Steroids
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Endocrine
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Q: A 46,XX newborn is born at 38 weeks' gestation with ambiguous genitalia. Laboratory studies show a blood glucose of 65 mg/dL, potassium of 5.5 mEq/L, and salt wasting. Serum 17-OH progesterone is markedly increased. Which adrenal enzyme deficiency is the most likely diagnosis?
ReplyDeleteA: 21-hydroxylase deficiency
Glucocorticoids are distinguished from mineralocorticoids and sex steroids by their ..... Glucocorticoids may be used in low doses in adrenal insufficiency. testoterone
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