- SILENT: 3rd position = NO CHANGES
- MISSENSE: all the misses world are "beuty" = similar.
- Similar structure of amino acids.
- Sickle Cell.
- FRAMESHIFT: short protein and unfunctional.
- NO SENSE: STOP codon.
Silent < Missense < Frameshift < No sense
- It can occur in DNA or RNA.
- SPLICESOME: B-thalassemia, SLE, Marfan's, T-cell disease, Gaucher's
Q: The image shows a mutation that can cause hemoglobinopathy:
ReplyDelete- mRNA transcript of normal gene UCU UCA CGU
- mRNA transcript of mutation UCU UAA
This is an example of which type of mutation?
A: Nonsense mutation.