Thursday, August 22, 2013

Sympathetic Adrenergic Agonists and Antagonists


  1. Q: An ophthalmologist puts a drop of phenylephrine and a drop of tropicamide in the same eye at the same time. Which of the following is the most likely effect?

    A: Mydriasis and loss of accomodation

  2. Q: A 48-year-old-man comes to the physician for a routine examination following treatment with an anti-hypertensive medication. His blood pressure is 123/78 mm Hg. Physical examination shows no abnormalities. Laboratory studies show: total cholesterol 280 mg/dL, HDL 34 mg/dL, LDL 188 mg/dL, and triglycerides 191 mg/dL. He states that his lipid panel was normal prior to the start of the anti-hypertensive medication. Which anti-hypertensive medications is most likely responsible for these findings in this patient?

    A: Metropolol is a beta-adrenergic blocking agent that is known to cause dyslipidemias in patients. Althoug thiazides also cause hyperlipidemias.