Thursday, April 18, 2013

Basal Ganglia

Excellent video explanation, the mind map for this video is above to improve the understanding and memorization...

Parkinson's disease: The symptoms are causes by loss of inhibiting of putamen. Without putamen inhibition (Putamen overworks), this overinhibits the globus pallidus externa, causing loss of inhibition to the subthalamic nucleus, producing a overstimulation of globus pallidus internal with fallowed inhibition of thalamus causing hypokinesia?

Q1: Patient with involuntary large, finging movements of her right arm. CT scan shows a lacunar infarct of the subthalamic nucleus. What is the direct effect of activation of the subthalamic nucleus in a healthy brain?
A1: Excitation of the internal segment of the globus pallidus

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